2-(2,6-二氧代-3-哌啶基)-4-羟基异吲哚啉-1,3-二酮
Thalidomide-4-OH | Cereblon ligand 2 | E3 ligase Ligand 2)
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Product Name Thalidomide-4-OH | Cereblon ligand 2 | E3 ligase Ligand 2)
CAS5054-59-1
FormulaC13H10N2O5
MW274.23
MDLMFCD03699892
AppearanceWhite to gray powder
Storage condition4°C, stored under nitroge
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Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.


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History
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