| Product Name | 7-Ethyl-10-hydroxycamptothecin | SN-38 | NK012 |
|---|---|
| CAS | 86639-52-3 |
| Formula | C22H20N2O5 |
| MW | 392.40 |
| MDL | MFCD00871873 |
| Appearance | Light yellow crystalline powder |
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.
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