雷公藤甲素 (雷藤素甲;雷公藤内酯醇;雷公藤多甙)
Triptolide (PG490)
Herbleader
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10 mg 20 mg
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$98.00
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$158.00
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Product Overview
Product Name Triptolide (PG490)
CAS38748-32-2
FormulaC20H24O6
MW360.40
MDLMFCD00210565
Appearancewhite solid powder
Storage condition 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.

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Triptolide (PG490)