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(2S,3R,4S,5S,6R)-2-(((2S,3R,4S,5S,6R)-4,5-二羟基-2-(((3R,6R)-2-羟基-6-((3S,8S,9R,10R,11R,13R,14S,17R)-11-羟基-4,4,9,13,14-五甲基-3-(((2R,3R,4S,5S,6R)-3,4,5-三羟基-6-((((2R,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)甲基)四氢-2H-吡喃-2-基)氧基)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊[a]菲-17-基)-2-甲基庚-3-基)氧基)-6-((((2R,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-yl)氧基)甲基)四氢-2H-吡喃-3-基)氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇; 罗汉果苷V; 罗汉果甜苷V; 罗汉果皂苷V

Mogroside V

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Catalog No：HL1227

CAS No.：88901-36-4

MDLNo：MFCD00238649

Formula：C60H102O29

MW：1,287.43

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Product Name	Mogroside V
CAS	88901-36-4
Formula	C60H102O29
MW	1,287.43
MDL	MFCD00238649
Appearance	White to off-white powder
Storage condition	4°C, protect from light

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Mogroside V, a key active component in Siraitiae Fructus, is a potent non-sugar sweetener with an in vitro AMPK-activating effect. It demonstrates anti-inflammatory properties in murine macrophages and a murine ear edema model, and it may protect against LPS-induced airway inflammation in acute lung injury (ALI) models. This triterpenoid glycoside also possesses antioxidant capabilities, mitigates intracellular reactive oxygen species (ROS) levels, and enhances mitochondrial function. Mogroside V exhibits anti-oxidative, anti-diabetic, and anti-carcinogenic effects, making it a valuable compound for diabetes research. It is particularly relevant for pancreatic cancer models, where it inhibits tumor growth.

Related literature

Mogroside V improves porcine oocyte in vitro maturation and subsequent embryonic development.

PMID: 31518726 DOI: 10.1016/j.theriogenology.2019.09.010

The metabolism of a natural product mogroside V, in healthy and type 2 diabetic rats.

PMID: 29428672 DOI: 10.1016/j.jchromb.2018.02.002

In vitro AMPK activating effect and in vivo pharmacokinetics of mogroside V, a cucurbitane-type triterpenoid from Siraitia grosvenorii fruits[J].

DOI:10.1039/C5RA23275A

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Mogroside V

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