异紫堇定碱; 右旋异紫堇定
(+)-Isocorynoline (Synonyms: Isocorydine)
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Product Name (+)-Isocorynoline (Synonyms: Isocorydine)
CAS475-67-2
FormulaC20H23NO4
MW341.40
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Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.
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History
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