芥芬胺; 蒜黎芦碱
Jervine (Synonyms: 11-Ketocyclopamine)
Herbleader
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Product Name Jervine (Synonyms: 11-Ketocyclopamine)
CAS469-59-0
FormulaC27H39NO3
MW425.60
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Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM. Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties.
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History
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