Product Name | 20(S)-Ginsenoside Rh2 |
---|---|
CAS | 78214-33-2 |
Formula | C36H62O8 |
MW | 622.87 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Ginsenoside Rh2, a naturally occurring steroid glycoside and an aldose reductase inhibitor, is isolated from the root of ginseng and has a variety of biological effects. Caspase-8 and Caspase-9 activation can be induced by ginsenoside Rh2. Ginsenoside Rh2 induces apoptosis in cancer cells via multiple pathways. In Alzheimer's disease models, it also lowers amyloid-β levels, induces β -cell proliferation, and inhibits osteoclastogenesis by stifling RANKL-induced osteoclast differentiation.
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