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MMAF Hydrochloride;Monomethylauristatin F Hydrochloride

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Catalog No:CL1348A CAS No.:1415246-68-2 MDLNo: Formula:C39H66ClN5O8 MW:768.42
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5 mg 3-5days $200.00 Visible after login
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10 mg 3-5days $325.00 Visible after login
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25 mg 3-5days $500.00 Visible after login
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Chemical safety data sheet(MSDS)

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Product Overview
Product Name MMAF Hydrochloride;Monomethylauristatin F Hydrochloride
CAS1415246-68-2
FormulaC39H66ClN5O8
MW768.42
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Monomethyl auristatin F (MMAF) HCl is a highly potent tubulin inhibitor and an antineoplastic agent used as a warhead in ADCs (antibody-drug conjugates) such as vorsetuzumab mafodotin and SGN-CD19A. Mafodotin is the term used in International Nonproprietary Names for MMAF-antibody-conjugates to describe MMAF along with its antibody-binding structure. As opposed to auristatin F, which has two methyl substituents in its N-terminal amino group, MMAF is actually desmethyl-auristatin F.

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