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MMAF sodium (Monomethylauristatin F sodium)

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Catalog No:CL1348B CAS No.:1799706-65-2 MDLNo: Formula:C39H64N5NaO8 MW:753.94
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5 mg 3-5days $200.00 Visible after login
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10 mg 3-5days $375.00 Visible after login
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25 mg 3-5days $650.00 Visible after login
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Chemical safety data sheet(MSDS)

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Product Overview
Product Name MMAF sodium (Monomethylauristatin F sodium)
CAS1799706-65-2
FormulaC39H64N5NaO8
MW753.94
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Monomethyl auristatin F (MMAF) sodium is a highly potent tubulin inhibitor and an antineoplastic agent used as a warhead in ADCs (antibody-drug conjugates) such as vorsetuzumab mafodotin and SGN-CD19A. MMAF plus its attachment structure to the antibody are referred to as mafodotin in the International Nonproprietary Names for MMAF-antibody-conjugates. Since the N-terminal amino group of MMAF only has one methyl substituent rather than two, as it does in auristatin F itself, it is actually desmethyl-auristatin F.

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