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Etoricoxib (MK-663; MK-0663)

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Catalog No:CL1843 CAS No.:202409-33-4 MDLNo: Formula:C18H15ClN2O2S MW:358.84
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25 mg 3-5days $100.00 Visible after login
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50 mg 3-5days $163.00 Visible after login
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100 mg 3-5days $213.00 Visible after login
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Chemical safety data sheet(MSDS)

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Product Overview
Product Name Etoricoxib (MK-663; MK-0663)
CAS202409-33-4
FormulaC18H15ClN2O2S
MW358.84
AppearanceLight yellow to yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Etoricoxib (also known as MK-0663) is a non-steroidal anti-inflammatory drgu (NSAID) which acts as a selective and orally bioactive COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. Etoricoxib is a synthetic NSAID with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib binds specifically to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.

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