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PF-03814735

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Catalog No：CL2486 CAS No.：942487-16-3 MDLNo： Formula：C23H25F3N6O2 MW：474.48

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$160.00	Visible after login	- +
10 mg	3-5days	$457.00	Visible after login	- +
5 mg	3-5days	$460.00	Visible after login	- +

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Product Overview

Product Name	PF-03814735
CAS	942487-16-3
Formula	C23H25F3N6O2
MW	474.48
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

PF-03814735 (PF03814735) is a reversible, orally bioavailable, and ATP-competitive inhibitor of Aurora A/B kinases with potential antitumor activity. It inhibits Aurora A/B with IC50of 0.8 nM and 5 nM, respectively. PF-03814735 showed less potency against Flt3, FAK, TrkA, Met and FGFR1. It exhibits potent in vitro antiproliferative activity and high in vivo antitumor efficacy.

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History

CLP1003

Rink Amide-AM Resin; 4-(2′,4′-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxyacetamido-aminomethyl resin

183599-10-2 Loading: 0.3~0.8mmol/g,Cross-Linking: 1%DVB

CL2486

PF-03814735

942487-16-3 98+%