PF-04620110

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$138.00	Visible after login	- +
10 mg	3-5days	$200.00	Visible after login	- +
25 mg	3-5days	$365.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5days

$138.00

Visible after login

- +

10 mg

3-5days

$200.00

Visible after login

- +

25 mg

3-5days

$365.00

Visible after login

- +

Product Overview

Product Name	trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid
CAS	1109276-89-2
Formula	C21H24N4O4
MW	396.44
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

PF-04620110 (PF04620110; PF 04620110) is a novel, potent, orally bioactive, and selective diglyceride acyltransferase-1 (DGAT1) inhibitor with the potential to treat type 2 diabetes mellitus. It inhibits DGAT1 with an IC50 of 19 nM. PF-04620110 has been advanced to clinical trials on the basis of the excellent pharmacologic and pharmacokinetic profiles. F-04620110 shows high selectivity versus a broad panel of off-target pharmacologic end points. In vivo DGAT-1 inhibition has been demonstrated through reduction of plasma triglyceride levels in rodents at doses of ≥0.1 mg/kg following a lipid challenge.

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History

CL2505

trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid

1109276-89-2 98+%

trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid

Chemical safety data sheet(MSDS)