Product Name | 7-Epi-10-Deacetyl Paclitaxel |
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CAS | 78432-77-6 |
Formula | C45H49NO13 |
MW | 811.87 |
Appearance | White to off-white powder |
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Product Name | 7-Epi-10-Deacetyl Paclitaxel |
---|---|
CAS | 78432-77-6 |
Formula | C45H49NO13 |
MW | 811.87 |
Appearance | White to off-white powder |
10-deacetyl Paclitaxel (10-DAP) is a taxane and precursor in the semisynthetic synthesis of paclitaxel that has been found in Taxus and has anticancer activity. It is cytotoxic to KB carcinoma cells (EC50 = 0.027 μg/ml).10-DAP (16 mg/kg) reduces tumor growth in the PS mouse lymphocytic leukemia model.