Product Name | Bortezomib (PS-341) |
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CAS | 179324-69-7 |
Formula | C19H25BN4O4 |
MW | 384.24 |
Appearance | White to off-white solid |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
100 mg | In-stock | $300.00 | Visible after login | |
500 mg | In-stock | $900.00 | Visible after login |
Product Name | Bortezomib (PS-341) |
---|---|
CAS | 179324-69-7 |
Formula | C19H25BN4O4 |
MW | 384.24 |
Appearance | White to off-white solid |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Bortezomib is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.