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Lenalidomide (CC-5013)

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Catalog No:CL1035 CAS No.:191732-72-6 MDLNo: Formula:C13H13N3O3 MW:259.26
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500 mg 3-5days $320.00 Visible after login
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1 g 3-5days $400.00 Visible after login
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5 g 3-5days $1200.00 Visible after login
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Product Overview
Product Name Lenalidomide (CC-5013)
CAS191732-72-6
FormulaC13H13N3O3
MW259.26
AppearanceOff-white to light yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Lenalidomide is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.

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