Home > Category > Signaling Pathways > Membrane Transporter/Ion Channel > P-glycoprotein > Valspodar; PSC 833; PSC-833; PSC833; 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A

Valspodar; PSC 833; PSC-833; PSC833; 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A

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Catalog No:CL1078 CAS No.:121584-18-7 MDLNo: Formula:C63H111N11O12 MW:1214.62
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Product Overview
Product Name Valspodar; PSC 833; PSC-833; PSC833; 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A
CAS121584-18-7
FormulaC63H111N11O12
MW1214.62
AppearanceWhite to yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Valspodar, also known as PSC-833, is an analogue of cyclosporin-A. Valspodar inhibits p-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activity of some drugs in some drug-resistant tumor cells. This agent also induces caspase-mediated apoptosis.

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