AOH1996/N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	In-stock	$900.00	Visible after login	- +
10 mg	In-stock	$1360.00	Visible after login	- +
25 mg	In-stock	$2500.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

In-stock

$900.00

Visible after login

- +

10 mg

In-stock

$1360.00

Visible after login

- +

25 mg

In-stock

$2500.00

Visible after login

- +

Product Overview

Product Name	AOH1996/N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide
CAS	2089314-64-5
Formula	C26H22N2O4
MW	426.46
Appearance	White powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

AOH1996 is an inhibitor of proliferating cell nuclear antigen (PCNA).It binds to PCNA in a thermal shift assay. AOH1996 (500 nM) induces apoptosis in SK-N-DZ neuroblastoma cells but not 7SMOO32 normal neural crest stem cells. It induces DNA damage in SK-N-AS neuroblastoma cells expressing wild-type DNA-directed RNA polymerase II subunit RPB1 but not in SK-N-AS cells expressing RPB1Y418A. AOH1996 (40 mg/kg) decreases tumor volume in SK-N-BE(2)-C neuroblastoma, MDA-MB-468 breast cancer, and NCI H82 small cell lung cancer mouse xenograft models.

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History

CL1093

AOH1996/N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide

2089314-64-5 98+%

AOH1996/N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)