MMAF sodium (Monomethylauristatin F sodium)

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Product Overview

Product Name	MMAF sodium (Monomethylauristatin F sodium)
CAS	1799706-65-2
Formula	C39H64N5NaO8
MW	753.94
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Monomethyl auristatin F (MMAF) sodium is a highly potent tubulin inhibitor and an antineoplastic agent used as a warhead in ADCs (antibody-drug conjugates) such as vorsetuzumab mafodotin and SGN-CD19A. MMAF plus its attachment structure to the antibody are referred to as mafodotin in the International Nonproprietary Names for MMAF-antibody-conjugates. Since the N-terminal amino group of MMAF only has one methyl substituent rather than two, as it does in auristatin F itself, it is actually desmethyl-auristatin F.

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History

CL1348B

MMAF sodium (Monomethylauristatin F sodium)

1799706-65-2 98+%

MMAF sodium (Monomethylauristatin F sodium)

Chemical safety data sheet(MSDS)