Home > Category > Signaling Pathways > PROTAC > Ligands for E3 Ligase > Pomalidomide; 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione

Pomalidomide; 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione

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Catalog No：CL2201 CAS No.：19171-19-8 MDLNo： Formula：C13H11N3O4 MW：273.24

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
200 mg	3-5days	$220.00	Visible after login	- +
500 mg	3-5days	$250.00	Visible after login	- +
1 g	3-5days	$300.00	Visible after login	- +

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Product Overview

Product Name	Pomalidomide; 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
CAS	19171-19-8
Formula	C13H11N3O4
MW	273.24
Appearance	Yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.

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CL2201

Pomalidomide; 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione

19171-19-8 98+%