E-64; 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-(2S,3S)-oxiranecarboxylic acid;trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane

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Product Overview

Product Name	E-64; 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-(2S,3S)-oxiranecarboxylic acid;trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane
CAS	66701-25-5
Formula	C15H27N5O5
MW	357.41
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

E-64 is a potent, and irreversible inhibitor of cysteine proteases with IC50 values for inhibiting cathepsins K, S, and L, in vitro, are 1.4, 4.1, and 2.5 nM, respectively. E-64 improves the preimplantation development of bovine somatic cell nuclear transfer embryos.

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History

CL2488

E-64; 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-(2S,3S)-oxiranecarboxylic acid;trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane

66701-25-5 98+%

E-64; 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-(2S,3S)-oxiranecarboxylic acid;trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane

Chemical safety data sheet(MSDS)