Home > Category > Signaling Pathways > Protein Tyrosine Kinase/RTK > IGF-1R > Dalotuzumab (Anti-IGF1R / CD221)

Dalotuzumab (Anti-IGF1R / CD221)

ChemLeader 95+%

Catalog No：CLA1248 CAS No.：1005389-60-5 MDLNo： Formula： MW：

Collect Share

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$720.00	Visible after login	- +
5 mg	3-5days	$1600.00	Visible after login	- +
10 mg	3-5days	$2900.00	Visible after login	- +
50 mg	3-5days	$12000.00	Visible after login	- +
100 mg	3-5days	$18000.00	Visible after login	- +

Chemical safety data sheet(MSDS)

Download MSDS

Inquiry Add To Cart

Product Overview
Related documents
Product details
Related literature

Product Overview

Product Name	Dalotuzumab (Anti-IGF1R / CD221)
CAS	1005389-60-5
Storage condition	Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light.

Product details

Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R . Dalotuzumab acts by inhibiting IGF-1 - and IGF-2 -mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.

Related literature

Sorry, there is no relevant literature

Sorry, no related items

History

CLA1248

Dalotuzumab (Anti-IGF1R / CD221)

1005389-60-5 95+%