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Triptolide (PG490)

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Catalog No：HL1019 CAS No.：38748-32-2 MDLNo： Formula：C20H24O6 MW：360.40

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
10 mg	In-stock	$350.00	Visible after login	- +
20 mg	In-stock	$500.00	Visible after login	- +

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Product Overview

Product Name	Triptolide (PG490)
CAS	38748-32-2
Formula	C20H24O6
MW	360.40
Appearance	white solid powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.

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HL1019

Triptolide (PG490)

38748-32-2 98+%