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Nintedanib(BIBF 1120)

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Catalog No:CL1034 CAS No.:656247-17-5 MDLNo: Formula:C31H33N5O4 MW:539.62
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Product Overview
Product Name Nintedanib(BIBF 1120)
CAS656247-17-5
FormulaC31H33N5O4
MW539.62
AppearanceYellow crystalline powder
Product details

Nintedanib, also known as BIBF 1120, is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor receptor (PDGFR). Intedanib selectively binds to and inhibits vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet-derived growth factor receptor (PDGFR) tyrosine kinases, which may result in the induction of endothelial cell apoptosis; a reduction in tumor vasculature; and the inhibition of tumor cell proliferation and migration

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