Product Name | Belinostat (PXD101) |
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CAS | 866323-14-0 |
Formula | C15H14N2O4S |
MW | 318.35 |
Appearance | Off-white crystalline powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
50 mg | In-stock | $220.00 | Visible after login | |
100 mg | In-stock | $300.00 | Visible after login | |
500 mg | In-stock | $1000.00 | Visible after login |
Product Name | Belinostat (PXD101) |
---|---|
CAS | 866323-14-0 |
Formula | C15H14N2O4S |
MW | 318.35 |
Appearance | Off-white crystalline powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.