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Belinostat (PXD101)

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Catalog No:CL1043 CAS No.:866323-14-0 MDLNo: Formula:C15H14N2O4S MW:318.35
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Product Overview
Product Name Belinostat (PXD101)
CAS866323-14-0
FormulaC15H14N2O4S
MW318.35
AppearanceOff-white crystalline powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.  

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