Home > Category > Signaling Pathways > Cell Cycle > CDK > Tagtociclib (PF-07104091)

Tagtociclib (PF-07104091)

ChemLeader 98+%

Catalog No：CL1103 CAS No.：2460249-19-6 MDLNo： Formula：C19H28N6O4 MW：404.46

Collect Share

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Chemical safety data sheet(MSDS)

Download MSDS

Certificate Of Authenticity(CPA)

Download COA

Inquiry Add To Cart

Product Overview
Related documents
Product details
Related literature

Product Overview

Product Name	Tagtociclib (PF-07104091)
CAS	2460249-19-6
Formula	C19H28N6O4
MW	404.46
Appearance	Solid powder
Storage condition	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Product details

Tagtociclib, also known as PF-07104091, is an orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity. Upon administration, CDK2 inhibitor PF-07104091 selectively targets, binds to and inhibits the activity of CDK2. This may lead to cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. CDKs are serine/threonine kinases that are important regulators of cell cycle progression and cellular proliferation and are frequently overexpressed in tumor cells. CDK2/cyclin E complex plays an important role in retinoblastoma (Rb) protein phosphorylation and the G1-S phase cell cycle transition. CDK2/cyclin A complex plays an important role in DNA synthesis in S phase and the activation of CDK1/cyclin B for the G2-M phase cell cycle transition.

Related literature

Sorry, there is no relevant literature

Sorry, no related items

History

CL1103

Tagtociclib (PF-07104091)

2460249-19-6 98+%