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Tofacitinib (Tasocitinib; CP-690550)

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Catalog No:CL1120 CAS No.:477600-75-2 MDLNo: Formula:C16H20N6O MW:312.37
Size Availability Price(USD) VIP Price (USD) Quantity
20 mg 3-5days $280.00 Visible after login
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50 mg 3-5days $350.00 Visible after login
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100 mg 3-5days $450.00 Visible after login
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Product Overview
Product Name Tofacitinib (Tasocitinib; CP-690550)
CAS477600-75-2
FormulaC16H20N6O
MW312.37
AppearanceWhite or off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.

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