Product Name | Tofacitinib (Tasocitinib; CP-690550) |
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CAS | 477600-75-2 |
Formula | C16H20N6O |
MW | 312.37 |
Appearance | White or off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
20 mg | 3-5days | $280.00 | Visible after login | |
50 mg | 3-5days | $350.00 | Visible after login | |
100 mg | 3-5days | $450.00 | Visible after login |
Product Name | Tofacitinib (Tasocitinib; CP-690550) |
---|---|
CAS | 477600-75-2 |
Formula | C16H20N6O |
MW | 312.37 |
Appearance | White or off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.