MMAF Hydrochloride;Monomethylauristatin F Hydrochloride

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Availability

Price(USD)

VIP Price (USD)

Quantity

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Product Overview

Product Name	MMAF Hydrochloride;Monomethylauristatin F Hydrochloride
CAS	1415246-68-2
Formula	C39H66ClN5O8
MW	768.42
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Monomethyl auristatin F (MMAF) HCl is a highly potent tubulin inhibitor and an antineoplastic agent used as a warhead in ADCs (antibody-drug conjugates) such as vorsetuzumab mafodotin and SGN-CD19A. Mafodotin is the term used in International Nonproprietary Names for MMAF-antibody-conjugates to describe MMAF along with its antibody-binding structure. As opposed to auristatin F, which has two methyl substituents in its N-terminal amino group, MMAF is actually desmethyl-auristatin F.

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History

CL1348A

MMAF Hydrochloride;Monomethylauristatin F Hydrochloride

1415246-68-2 98+%

MMAF Hydrochloride;Monomethylauristatin F Hydrochloride

Chemical safety data sheet(MSDS)