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LDN-193189(DM3189)

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Catalog No：CL1542 CAS No.：1062368-24-4 MDLNo： Formula：C25H22N6 MW：406.48

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
10 mg	In-stock	$520.00	Visible after login	- +
20 mg	In-stock	$1160.00	Visible after login	- +
50 mg	In-stock	$2000.00	Visible after login	- +

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Product Overview

Product Name	LDN-193189(DM3189)
CAS	1062368-24-4
Formula	C25H22N6
MW	406.48
Appearance	Light yellow to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.

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CL1542

LDN-193189(DM3189)

1062368-24-4 98+%