Product Name | Indacaterol Maleate |
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CAS | 753498-25-8 |
Formula | C28H32N2O7 |
MW | 508.56 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
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Product Name | Indacaterol Maleate |
---|---|
CAS | 753498-25-8 |
Formula | C28H32N2O7 |
MW | 508.56 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Indacaterol Maleate (formerly known as QAB149; QAB-149; Onbrez Breezhale; arcapta neohaler; Onbrez), the maleate salt of indacaterol, is an approved anti-COPD (chronic obstructive pulmonary disease) drug acting as an ultra-long-acting β-adrenoceptor agonist developed by Novartis. β-adrenoceptor is activated with a pKi of 7.36 in. The FDA approved indacaterol in 2009 to treat chronic obstructive pulmonary disease (COPD). Using a dry powder inhaler, the aerosol formulation is administered. When Chinese hamster ovary cells are transfected with human β2 adrenoceptors and have a pEC50 of 8.06, indacaterol inhibits the production of cAMP.