Resatorvid | TAK-242 | CLI-095 | CAS 243984-11-4

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$200.00	Visible after login	- +
10 mg	3-5days	$286.00	Visible after login	- +

Product Overview

Product Name	Resatorvid (Synonyms: TAK-242; CLI-095;(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate)
CAS	243984-11-4
Formula	C15H17ClFNO4S
MW	361.82
Appearance	Off-white to yellow solid
Storage condition	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Security information

Product details

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.
Tags: buy Resatorvid (TAK-242) | purchase Resatorvid (TAK-242) | Resatorvid (TAK-242) cost | order Resatorvid (TAK-242) | Resatorvid (TAK-242) chemical structure | Resatorvid (TAK-242) in vivo | Resatorvid (TAK-242) in vitro | Resatorvid (TAK-242) formula | Resatorvid molecular weight

Related literature

The anticancer effect of the TLR4 inhibition using TAK-242 (resatorvid) either as a single agent or in combination with chemotherapy: A novel therapeutic potential for breast cancer.

PMID: 31535397 DOI: 10.1002/jcb.29397