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Bumetanide (Synonyms: Ro 10-6338; PF 1593)

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Catalog No:CL1023 CAS No.:28395-03-1 MDLNo:MFCD00078949 Formula:C17H20N2O5S MW:364.42
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Product Overview
Product Name Bumetanide (Synonyms: Ro 10-6338; PF 1593)
CAS28395-03-1
FormulaC17H20N2O5S
MW364.42
MDLMFCD00078949
Product details

Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively.

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