Product Name | Mirdametinib (PD0325901) |
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CAS | 391210-10-9 |
Formula | C16H14F3IN2O4 |
MW | 482.19 |
Appearance | White powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
10 mg | In-stock | $118.00 | Visible after login | |
50 mg | In-stock | $226.00 | Visible after login | |
100 mg | In-stock | $336.00 | Visible after login |
Product Name | Mirdametinib (PD0325901) |
---|---|
CAS | 391210-10-9 |
Formula | C16H14F3IN2O4 |
MW | 482.19 |
Appearance | White powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Mirdametinib, also known as PD-0325901, is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors.