VX-702; 6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide;CAS: VX-702

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Product Overview

Product Name	VX-702
CAS	745833-23-2
Formula	C19H12F4N4O2
MW	404.32
MDL	MFCD11616590
Appearance	White to off-white powder

Product details

VX-702 is recognized as a highly selective inhibitor of p38α MAPK, with a 14-fold greater potency against p38α compared to p38β. This second-generation inhibitor is known for its high specificity and oral activity, making it a valuable tool in the research and potential treatment of inflammatory diseases, particularly rheumatoid arthritis.

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PMID: 26289811 PMCID: PMC4560789 DOI: 10.1038/ncomms9039

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History

CL1115

VX-702

745833-23-2 98+%