Lurbinectedin | PM01183 | LY-01017 | Tryptamicidin | CAS 497871-47-3

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Product Overview

Product Name	Lurbinectedin \| PM01183 \| LY-01017 \| Tryptamicidin
CAS	497871-47-3
Formula	C41H44N4O10S
MW	784.87
MDL	MFCD22665743
Appearance	White to light yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

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Product details

Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC₅₀ values of 1.25 and 1.16 nM, respectively.

Related literature

PM01183, a new DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity.

PMID: 20977459 PMCID: PMC2998690 DOI: 10.1111/j.1476-5381.2010.00945.x