Product Name | Polmacoxib |
---|---|
CAS | 301692-76-2 |
Formula | C18H16FNO4S |
MW | 361.39 |
Appearance | Light yellow to green yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
5 mg | 3-5days | $96.00 | Visible after login | |
10 mg | 3-5days | $156.00 | Visible after login |
Product Name | Polmacoxib |
---|---|
CAS | 301692-76-2 |
Formula | C18H16FNO4S |
MW | 361.39 |
Appearance | Light yellow to green yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.
CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models.
PMID: 28421763 DOI: 10.1021/acs.jmedchem.7b00010
ynthetic Approaches to the New Drugs Approved During 2015
PMID: 28421763 DOI: 10.1021/acs.jmedchem.7b00010