Home > Category > Signaling Pathways > MAPK/ERK Pathway > ERK > Ulixertinib hydrochloride (Synonyms: BVD-523 hydrochloride; VRT752271 hydrochloride;Ulixertinib HCl salt) ; (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride.

Ulixertinib hydrochloride (Synonyms: BVD-523 hydrochloride; VRT752271 hydrochloride;Ulixertinib HCl salt) ; (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride.

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Catalog No:CL1281A CAS No.:1956366-10-1 MDLNo:MFCD22543853 Formula:C21H23Cl3N4O2 MW:469.79
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Product Overview
Product Name Ulixertinib hydrochloride (Synonyms: BVD-523 hydrochloride; VRT752271 hydrochloride;Ulixertinib HCl salt) ; (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride.
CAS1956366-10-1
FormulaC21H23Cl3N4O2
MW469.79
MDLMFCD22543853
Product details

Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.

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