NVP-AUY922 | Luminespib | AUY922 | VER-52296

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	NVP-AUY922 \| Luminespib \| AUY922 \| VER-52296
CAS	747412-49-3
Formula	C26H31N3O5
MW	465.54
Appearance	Light yellow to gray powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β (IC50=7.8/21 nM). Luminespib has antitumor activity and is used in studies of head and neck tumors, among others.

Related literature

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis.

PMID: 18413753 DOI: 10.1158/0008-5472.CAN-07-5256

Heat shock protein-90 inhibitor, NVP-AUY922, is effective in combination with NSC 118218 against chronic lymphocytic leukemia cells cultured on CD40L-stromal layer and inhibits their activated/proliferative phenotype.

PMID: 22646928 DOI: 10.3109/10428194.2012.698278

Stoeltzing O.Targeting HSP90 by the novel inhibitor NVP-AUY922 reduces growth and angiogenesis of pancreatic cancer.

PMID: 22753713

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History

CL1282

NVP-AUY922 | Luminespib | AUY922 | VER-52296

747412-49-3 98+%