Product Name | CEP-28122 mesylate salt (Synonyms:CEP-28122 (Mesylate salt)) |
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CAS | 2070009-30-0 |
Formula | C29H39ClN6O6S |
MW | 635.17 |
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Product Name | CEP-28122 mesylate salt (Synonyms:CEP-28122 (Mesylate salt)) |
---|---|
CAS | 2070009-30-0 |
Formula | C29H39ClN6O6S |
MW | 635.17 |
CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.