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Siponimod Hemifumarate | BAF-312 Hemifumarate

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Catalog No:CL1367A CAS No.:1234627-85-0 MDLNo: Formula:C29H35F3N2O3·1/2C4H4O4 MW:574.63 | 516.61(free)
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5 mg 3-5days $316.00 Visible after login
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10 mg 3-5days $446.00 Visible after login
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Product Overview
Product Name Siponimod Hemifumarate | BAF-312 Hemifumarate
CAS1234627-85-0
FormulaC29H35F3N2O3·1/2C4H4O4
MW574.63 | 516.61(free)
Product details

Siponimod (BAF-312) hemifumarate is a potent and selective sphingosine-1-phosphate (S1P) receptor modulator. Siponimod hemifumarate is selective for S1P1 and S1P5 receptors over S1P2, S1P3, and S1P4 (EC50s of 0.39, 0.98, >10000, >1000, and 750 nM, respectively). Siponimod hemifumarate can be used for multiple sclerosis (MS) research.


Related literature

Mechanism of Siponimod: Anti-Inflammatory and Neuroprotective Mode of Action.

PMID: 30621015 PMCID: PMC6356776 DOI: 10.3390/cells8010024

Prospects of siponimod in secondary progressive multiple sclerosis.

PMID: 30038666 PMCID: PMC6050809 DOI: 10.1177/1756286418788013

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