Infigratinib | GJ-398 | NVP-BGJ398

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$66.00	Visible after login	- +
10 mg	3-5days	$108.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5days

$66.00

Visible after login

- +

10 mg

3-5days

$108.00

Visible after login

- +

Product Overview

Product Name	Infigratinib \| GJ-398 \| NVP-BGJ398
CAS	872511-34-7
Formula	C26H31Cl2N7O3
MW	560.48
Appearance	White to yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC₅₀s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

Related literature

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-me thyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor T

PMID: 21936542 DOI: 10.1021/jm2006222

Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple Negative Breast Cancer.

PMID: 29203461 PMCID: PMC5907916 DOI: 10.1158/2159-8290.CD-17-0679

Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells.

PMID: 23443805 DOI: 10.1158/1535-7163.MCT-12-0999

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History

CL1547

Infigratinib | GJ-398 | NVP-BGJ398

872511-34-7 98+%

Infigratinib | GJ-398 | NVP-BGJ398

Chemical safety data sheet(MSDS)