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Afatinib (Synonyms: BIBW 2992; 阿法替尼)

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Catalog No:CL1632 CAS No.:850140-72-6 MDLNo: MFCD12407405 Formula:C24H25ClFN5O3 MW:485.94
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100 mg In-stock $148.00 Visible after login
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500 mg In-stock $316.00 Visible after login
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1 g In-stock $450.00 Visible after login
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Product Overview
Product Name Afatinib (Synonyms: BIBW 2992; 阿法替尼)
CAS850140-72-6
FormulaC24H25ClFN5O3
MW485.94
MDL MFCD12407405
AppearanceWhite solid powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.

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