Product Name | ZM-447439 |
---|---|
CAS | 331771-20-1 |
Formula | C29H31N5O4 |
MW | 513.59 |
MDL | MFCD08703125 |
Appearance | White to gray powder |
Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
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Product Name | ZM-447439 |
---|---|
CAS | 331771-20-1 |
Formula | C29H31N5O4 |
MW | 513.59 |
MDL | MFCD08703125 |
Appearance | White to gray powder |
Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
ZM447439 is a potent, selective aurora-A and -B kinase inhibitor with potential anti-tumoral effects. It induces apoptosis in a concentration- and time-dependent manner. The IC50 values for aurora A and B are 110 nM and 130 nM, respectively.
Cell Cycle. 2008 May 15;7(10):1473-9.
PMID: 12719470 PMCID: PMC2172902 DOI: 10.1083/jcb.200208091