Fulvestrant | ICI 182780 | ZD 9238 | ZM 182780 |Estrogen/progestogen Receptor antagonist | CAS 129453-61-8 | Autophagy activator

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Product Overview

Product Name	Fulvestrant \| ICI 182780 \| ZD 9238 \| ZM 182780
CAS	129453-61-8
Formula	C32H47F5O3S
MW	606.77
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity.

Related literature

A potent specific pure antiestrogen with clinical potential.

PMID: 1855205

Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action.

PMID: 15094757 PMCID: PMC2750773 DOI: 10.1038/sj.bjc.6601629

MiR-214 increases the sensitivity of breast cancer cells to tamoxifen and fulvestrant through inhibition of autophagy.

PMID: 26666173 PMCID: PMC4678692 DOI: 10.1186/s12943-015-0480-4

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History

CL1655

Fulvestrant | ICI 182780 | ZD 9238 | ZM 182780

129453-61-8 99+%

Fulvestrant | ICI 182780 | ZD 9238 | ZM 182780

Chemical safety data sheet(MSDS)