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Product Overview

Product Name	Doxercalciferol (Synonyms:1α-Hydroxyvitamin D2)
CAS	54573-75-0
Formula	C28H44O2
MW	412.65
MDL	MFCD00871065
Appearance	White to off-white powder
Storage condition	-20°C, protect from light

Product details

Doxercalciferol, a synthetic analog of vitamin D2, functions as an activator of the vitamin D receptor. It exhibits the ability to suppress parathyroid synthesis and secretion, thereby preventing renal disease and making it a valuable therapeutic option for secondary hyperparathyroidism and metabolic bone disease.

Related literature

Vitamin D receptor signaling in podocytes protects against diabetic nephropathy.

PMID: 23123403 PMCID: PMC3507366 DOI: 10.1681/ASN.2012040383

Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism.

PMID: 21209008 PMCID: PMC3064139 DOI: 10.1152/ajprenal.00338.2010

Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats.

PMID: 18644798 DOI: 10.1093/ndt/gfn375