JNJ-38877605 | JNJ 38877605

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$126.00	Visible after login	- +
10 mg	3-5days	$218.00	Visible after login	- +

Product Overview

Product Name	JNJ-38877605 \| JNJ 38877605
CAS	943540-75-8
Formula	C19H13F2N7
MW	377.35
Appearance	Off-white to light yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Security information

Product details

JNJ-38877605 is an orally active ATP-competitive inhibitor of c-Met with an IC₅₀ of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. JNJ-38877605 inhibits c-Met phosphorylation and regulates lipid accumulation. JNJ-38877605 can be used for tumor and metabolic disease reseach.

Related literature

A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.

PMID: 21500189 DOI: 10.1002/ijc.26137

PMID: 21464397 DOI: 10.1093/jnci/djr093

PMID: 35101055 PMCID: PMC8802424 DOI: 10.1186/s12964-021-00818-8

PMID: 37175792 PMCID: PMC10179087 DOI: 10.3390/ijms24098086

History

CL1800

JNJ-38877605 | JNJ 38877605

943540-75-8 98+%

JNJ-38877605 | JNJ 38877605

Chemical safety data sheet(MSDS)