Varespladib | LY315920 | CAS 172732-68-2

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	In-stock	$88.00	Visible after login	- +
5 mg	In-stock	$106.00	Visible after login	- +
10 mg	In-stock	$206.00	Visible after login	- +
25 mg	3-5days	$308.00	Visible after login	- +

Size

Availability

Price(USD)

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Quantity

1 mg

In-stock

$88.00

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- +

5 mg

In-stock

$106.00

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- +

10 mg

In-stock

$206.00

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- +

25 mg

3-5days

$308.00

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- +

Product Overview

Product Name	Varespladib \| LY315920
CAS	172732-68-2
Formula	C21H20N2O5
MW	380.39
MDL	MFCD00944812
Appearance	White to yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.

Related literature

Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI.

PMID: 10027849

Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16.

PMID: 16249480 PMCID: PMC1473963 DOI: 10.1167/iovs.05-0627

Sorry, no related items

History

CL1901

Varespladib | LY315920

172732-68-2 98+%

Varespladib | LY315920

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)