Product Name | SB-505124 hydrochloride |
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CAS | 356559-13-2 |
Formula | C20H22ClN3O2 |
MW | 371.86 |
Appearance | Light yellow to green yellow powder |
Storage condition | 4°C, sealed storage, away from moisture |
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Product Name | SB-505124 hydrochloride |
---|---|
CAS | 356559-13-2 |
Formula | C20H22ClN3O2 |
MW | 371.86 |
Appearance | Light yellow to green yellow powder |
Storage condition | 4°C, sealed storage, away from moisture |
SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
PMID: 14978253 DOI: 10.1124/mol.65.3.744
PMID: 21031133 PMCID: PMC2956700