Sitaxsentan | IPI 1040 | TBC-11251

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Sitaxsentan (Synonyms: IPI 1040; TBC-11251)
CAS	184036-34-8
Formula	C18H15ClN2O6S2
MW	454.90
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Sitaxsentan (TBC-11251) is A selective endothelin A (ETA) receptor antagonist. Endothelin is an effective vasoconstrictor. Sitaxsentan blocks the binding of endothelin to its receptors, thereby eliminating the harmful effects of endothelin.

Related literature

STRIDE-4 investigators.Safety and efficacy of sitaxsentan 50 and 100 mg in patients with pulmonary arterial hypertension.

PMID: 22079088 DOI: 10.1016/j.pupt.2011.10.002

Sitaxsentan-induced acute severe hepatitis treated with glucocorticoid therapy.

PMID: 22332138 PMCID: PMC3298840 DOI: 10.1155/2012/567024

Effect of transition from sitaxsentan to ambrisentan in pulmonary arterial hypertension.

PMID: 21468170 PMCID: PMC3064451 DOI: 10.2147/VHRM.S15026

Successful treatment of portopulmonary hypertension with the selective endothelin receptor antagonist Sitaxentan.

PMID: 21451953 DOI: 10.1007/s00508-011-1540-4