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RG7388 | Idasanutlin

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Catalog No：CL2231 CAS No.：1229705-06-9 MDLNo： Formula：C31H29Cl2F2N3O4 MW：616.48

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	In-stock	$66.00	Visible after login	- +
10 mg	In-stock	$78.00	Visible after login	- +

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Product Overview

Product Name	RG7388 \| Idasanutlin
CAS	1229705-06-9
Formula	C31H29Cl2F2N3O4
MW	616.48
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Idasanutlin (RG7388) is a potent and selective MDM2 antagonist, inhibiting p53-MDM2 binding, with an IC₅₀ of 6 nM.

Related literature

Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development.

PMID: 23808545 DOI: 10.1021/jm400487c

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Preclinical optimization of MDM2 antagonist scheduling for cancer treatment by using a model-based approach.

PMID: 24812409 DOI: 10.1158/1078-0432.CCR-14-0460

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History

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