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Methotrexate

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Catalog No：CL2266 CAS No.：59-05-2 MDLNo： Formula：C20H22N8O5 MW：454.44

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
250 mg	In-stock	$125.00	Visible after login	- +
500 mg	In-stock	$200.00	Visible after login	- +
1 g	In-stock	$320.00	Visible after login	- +

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Product Overview

Product Name	Methotrexate
CAS	59-05-2
Formula	C20H22N8O5
MW	454.44
Appearance	Light yellow to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Methotrexate (MTX; alphamethopterin; amethopterin; methylaminopterin; CL-14377; NCIC04671; WR19039; NCI-C04671) is an FDA approved antineoplastic and immunosuppressant drug that belongs to the antimetabolite and antifolate class of drugs. It acts by inhibiting the metabolism of folic acid in activated peripheral T cells. Specifically, methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate (Amethopterin) is the disease-modifying antirheumatic drug (DMARD) of first choice for the treatment of RA in most countries worldwide. Methotrexate is an antineoplastic agent used to fight a number of different cancers, such as acute lymphoblastic leukemia and solid cancers.

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CL2266

Methotrexate

59-05-2 98+%